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Altogen Biosystems - Provider of Optimized Transfection Reagents


Altogen Biosystems is a well-known provider of transfection reagents and laboratory services world-wide for researchers in a variety of fields. Biology contract research services and products that are offered include assay development, reliable 28-day generation of stably-transfected cell lines, and _ laboratory services such as siRNA screening and ELISA assay development. For an A549 cell xenograftmodel, visit the Altogen Biosystems website.

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Evodiamine Triggers Apoptosis in A549 Cells

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Side Population Cells Present in A549 Cells

In the following study, researchers isolate and characterize side population (SP) cells that are present in the A549 cancer cell line. Fluorescence-activated cell sorting, assays, and a chemoresistance analysis were used to isolate and differentiate SP and non-SP (NSP) cells. Results show that SP cells account for 1.09% of live A549 cells and produced both SP and NSP cells. SP cells also exhibited improved invasive ability and had higher levels of chemoresistance compared to NSP cells in vitro.  Therefore, SP cells isolated from the A549 cell line exhibited more tumorigenicity, along with invasive ability and chemoresistance, than NSP cells. [ LINK ]
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